With the astonishing surge in cryptocurrency popularity in recent years, one can’t help but be mindful of the best-performing cryptocurrencies. As of September 22, 2025, here are the five best-performing cryptocurrencies with market caps above $10 billion:nn1. Bitcoin (BTC): No list is complete without the ‘original’ cryptocurrency- Bitcoin. Having a market cap well beyond any other digital currency, Bitcoin remains the pacesetter in the crypto universe.nn2. Ethereum (ETH): As the second-largest cryptocurrency by market cap, Ethereum continues to impress with its smart contract functionality.nn3. Binance Coin (BNB): Binance’s own native token has seen tremendous growth, largely due to its use within the Binance ecosystem.nn4. Cardano (ADA): Known for its scientific approach, Cardano continues to gain momentum in the crypto race.nn5. Polkadot (DOT): Rounding up the list is Polkadot, which aims at enabling a completely decentralized web where users are in control.nnPlease note that while these are currently the best performers, the highly volatile nature of cryptocurrencies can cause major shifts within short periods. Read More


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